Fig. 1: Distribution of Z-scores for each sample. | Nature Communications

Fig. 1: Distribution of Z-scores for each sample.

From: Analysis of erythrocyte signalling pathways during Plasmodium falciparum infection identifies targets for host-directed antimalarial intervention

Fig. 1

All antibody microarray signals from each sample (four from uRBCs and the mean signal for each iRBC harbouring parasites at the ring (n = 3), trophozoite (n = 3) and schizont stage (n = 2)) were compared with the uninfected erythrocyte mean value for each signal, and the Z-score determined for each phosphorylation-specific signal. The Z-score is defined as the number of SDs from the uRBC mean for each sample; a positive or negative value indicates the direction of the signal (increase or decrease, respectively) from the uRBC mean. No signals from the uRBC samples (n = 4) had associated Z-scores above 2 or below −2, whereas the three iRBC time points showed clear variations from uRBCs. Source data are provided as a Source Data file.

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