Table 1 Comparison of neutralization titers of patient sera analyzed by reporter assay and plaque reduction assay.

From: A high-throughput neutralizing antibody assay for COVID-19 diagnosis and vaccine evaluation

aSerum IDb

cPRNT50

cmNG-NT50

aSerum IDb

cPRNT50

cmNG-NT50

1 (d1)

<20

35

32 (d9)

640

762

2 (d5)

<20

38

33 (d8)

320

846

3 (d4)

<20

50

34 (d14)

800

873

4 (d5)

40

58

35 (d16)

1600

874

5 (d5)

20

66

36 (d17)

320

900

6 (d6)

80

74

37 (d9)

800

902

7 (d8)

80

77

38 (d15)

800

949

8 (d4)

80

85

39 (d15)

400

958

9 (d5)

80

85

40 (d18)

800

1016

10 (d1)

80

95

41 (d28)

1280

1072

11 (d6)

80

96

42 (d12)

800

1139

12 (NA)

160

96

43 (d13)

800

1145

13 (d6)

40

111

44 (d14)

800

1210

14 (d6)

40

114

45 (d31)

640

1213

15 (d1)

80

115

46 (d8)

800

1419

16 (d9)

160

120

47 (d14)

1600

1590

17 (d11)

80

132

48 (d21)

1600

1617

18 (d8)

80

200

49 (d12)

1600

2148

19 (NA)

160

261

50 (NA)

2560

2225

20 (d5)

160

318

51 (d20)

1600

2287

21 (d32)

320

329

52 (d8)

1600

2362

22 (d14)

160

365

53 (d12)

1600

2463

23 (d12)

160

366

54 (d18)

1600

2554

24 (d37)

320

456

55 (d16)

1600

2832

25 (NA)

320

474

56 (d15)

3200

3228

26 (d47)

320

525

57 (d31)

3200

4257

27 (d12)

640

617

58 (NA)

3200

5152

28 (d9)

320

649

59 (d8)

3200

5662

29 (d10)

640

681

60 (NA)

3200

5711

30 (d27)

320

721

61–120

<20

<20

31 (d9)

640

727

   
  1. aA total of 120 patient sera were analyzed, including 60 specimens from RT-PCR-confirmed patients (specimens 1–60) and 60 negative specimens (specimens 61–120) that were collected before COVID-19 pandemic (prepandemic).
  2. bSample collection days post after RT-PCR positive test are indicated in parentheses. For some COVID-19-positive specimens, the sample collection days post after RT-PCR positive test are not available (NA).
  3. cThe NT50 and PRNT50 values were derived from the reporter virus assay and conventional PRNT assay, respectively.