Fig. 2: The bias in the TCR repertoire of the translation-competent reservoir is due to clonal expansion. | Nature Communications

Fig. 2: The bias in the TCR repertoire of the translation-competent reservoir is due to clonal expansion.

From: Single-cell TCR sequencing reveals phenotypically diverse clonally expanded cells harboring inducible HIV proviruses during ART

Fig. 2

a, b Frequency of TRBV (a) and TRBJ (b) segment usage for the clonotypes identified by TCRβ sequencing in p24+ cells (red bars, n = 98 clonotypes) and p24− cells (blue bars, n = 353 clonotypes). c, d Association between the TRBV and TRBJ segments in individual p24 + (n = 636, c) and p24− (n = 357, d) cells from all participants (depicted by different colors). Connecting lines between the last two columns represent the number of individual associations. Large connecting lines denote a bias in the TCR repertoire. Source data are provided as a Source Data file.

Back to article page