Table 6 Comparative 3D–1D environmental profiles of hnRNPA2-LCD with pathogenic amyloids.
From: CryoEM structure of the low-complexity domain of hnRNPA2 and its conversion to pathogenic amyloid
Protein | Exposed to solvent (%) | Partially buried with high fractional environmental polarity (%) | Nonpolar buried (%) |
|---|---|---|---|
hnRNPA2-LCD | 35 | 32 | 4 |
Tau PHFs | 12 | 30 | 13 |
Aβ42 | 14 | 24 | 18 |
