Fig. 3: Trajectory analysis predicts precursors of MAIT and γδ T cells.
From: Single-cell RNA sequencing identifies shared differentiation paths of mouse thymic innate T cells
a, b Far left: UMAP plots of MAIT (a) and γδ T cells (b) show schematic representation of trajectories. Left to far right: t-SNE plots of MAIT (a) and γδ T cells (b) colored by cell clusters (left), Palantir pseudotime (right), and Palantir branching probabilities (far right). c Projections of the MAIT clusters to iNKT clusters by scamp-cluster. d Heat maps illustrate log2-transformed fold change of frequency of each TRGV/TRDV gene pair in a given cell cluster with respect to all γδ T cells.
