Fig. 7: Benchmarking MHC-II algorithm performance for prediction of peptide-binding affinity.

Scatterplots of algorithmic predictions versus measured IC50 values for 55 peptides assayed for binding to HLA-DR401 in fluorescence polarization competition assays, with lines of best fit and their associated coefficients of determination (R2). Asterisk denotes R2 values of negative correlations. Source data are provided as a Source Data file.