Table 1 Optimization of reaction conditionsa.

From: Catalytic asymmetric C–Si bond activation via torsional strain-promoted Rh-catalyzed aryl-Narasaka acylation

  1. aReaction conditions: 4a (0.10 mmol), 5a (0.15 mmol, 1.5 equiv), [Rh(CO)2Cl]2 (0.0025 mmol, 2.5 mol%), ligand (0.0105 mmol, 10.5 mol%) and base in 1,4-dioxane at 70 °C for 24 h.
  2. bKBr (30 mol%) was added.
  3. c30% (w/w) 4 Å MS was added.
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