Fig. 4: Inflammatory signature is inhibited in DFUs.
From: Deregulated immune cell recruitment orchestrated by FOXM1 impairs human diabetic wound healing
a Venn diagram of significantly regulated genes from oral, skin, and DFUs. b Top enriched GO processes from commonly regulated genes in oral and skin wounds compared to DFU specific genes (circled in yellow in part a) demonstrates processes involved in cellular proliferation and inflammation to be deregulated in DFUs compared to acute wounds (oral and skin). c Top canonical pathways involved in inflammation and d IPA-predicted network of inflammation in oral and skin compared to DFUs (n = 8 biologically independent samples) shows inhibition of cell proliferation and inflammation in DFUs compared to acute wounds (oral and skin).
