Table 3 Causal association between fasting glucose (all GWA significant) and risk of T2D.

From: An investigation of causal relationships between prediabetes and vascular complications

Method

OR

Lower 95% CI

Upper 95% CI

P value

Weighted median

1.55

1.23

1.94

1.67 × 10−4

IVW

2.26

1.37

3.74

1.43 × 10−3

Robust IVW

2.35

1.50

3.67

1.75 × 10−4

MR-Egger

0.46

0.19

1.12

0.09

InterceptMR-Egger

1.05

1.03

1.08

5.05 × 10−5

Robust MR-Egger

0.96

0.45

2.03

0.91

InterceptRobust MR-Egger

1.03

1.01

1.04

5.54 × 10−3

  1. n = 74. Results are from two-sample Mendelian randomization analyses and P values are two-sided. Results are unadjusted for multiple comparisons. Source data are provided as Source Data file.
  2. IVW inverse-variance weighted, OR odds ratio.
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