Fig. 5: Localization of hippocampal implants with 3T MRI imaging.
From: In vivo localization of chronically implanted electrodes and optic fibers in mice
a The postoperative CT image co-registered with the high signal-to-noise ratio (SNR) T1-weighted preoperative MRI image shows the hippocampus (white dashed box) in addition to the ventricles (blue arrows). The yellow arrow shows the position of an edge silicon probe in the hippocampus. Images from left to right, maximum intensity projection, sagittal slice, horizontal slice, and coronal slice. Yellow numbers refer to the corresponding stereotaxic coordinates in mm relative to Bregma. b Three-dimensional atlas co-registered with the postoperative CT image using the CT–MRI fusion technique with special attention to the alignment of the hippocampal structure. c Left, localized trajectory of the probe in the hippocampus. Right, layer-specific reconstruction of 32 contact sites (Or oriens layer, Py pyramidal layer, Rad stratum radiatum, LMol lacunosum moleculare, Mol molecular layer, GrDG granular layer, PoDG polymorph layer, DG dentate gyrus). CT and MRI images are shown in grayscale and goldscale, respectively.
