Fig. 5: Comparison of the hPolμΔ2 complementary DSB and other human or mouse Polμ crystal structures.
From: Structural snapshots of human DNA polymerase μ engaged on a DNA double-strand break
Superposition of hPolμΔ2 complementary DSB (colored as in Fig. 1a–b) with a hPolμΔ2 (gray, PDB ID code 4M0421) or c mouse Polμ (light blue, PDB ID code 2IHM19) 1nt-gapped SSB substrates, with zoomed-in view of superimposed human b or mouse d DNA substrates in stick. Red arrow and orange asterisk indicate the location of the broken template backbone and the hPolμΔ2 Loop2 deletion, respectively.
