Fig. 2: Water permeability of liposomes embedded with POCs.
a Permeabilities of POCs (CC3, FT-RCC3, CC5, and CC19) with loadings from 0 to 0.05 fmCLR measured under hypertonic conditions at 25 °C. b Representative stopped-flow traces from tests performed on liposomes embedded with CC3 of various fmCLRs. c Water permeabilities of liposomes with a combined fmCLR of 0.03 for CC1/CC3 mixture. Molar ratio of 0.0 refers to fmCLR of 0.03 for CC3 (no addition of CC1), and molar ratio of 1.0 refers to fmCLR of 0.03 for CC1 (no addition of CC3). d Single-channel water permeabilities of CC3 (this study) and synthetic channels with reported stopped-flow values4,8,9,10,11,12,13. Pink color indicates channels with total ion rejection while gray color indicates channels with partial to no cation rejection. Notably, the CC3 water channel can push the limit of ion-rejecting channel diameter from 2.8 to 5.8 Å, as indicated by the arrow. Error bars represent standard deviations of three independent replicates.
