Fig. 2: Biosynthetic genes of oxepinamide F and intermediates. | Nature Communications

Fig. 2: Biosynthetic genes of oxepinamide F and intermediates.

From: Oxepinamide F biosynthesis involves enzymatic d-aminoacyl epimerization, 3H-oxepin formation, and hydroxylation induced double bond migration

Fig. 2

a The oxepinamide biosynthetic gene cluster (opa) from A. ustus 3.3904. b HPLC analysis at 254 nm of the extracts after 7 day cultivation. c Structures of oxepinamide F (1), E (2), and 15-epi-oxepinamide E (5), as well as the CD spectra of 2 and 5 (200–400 nm). Blue double-headed arrows represent NOESY interactions.

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