Fig. 6: Validation of gut-microbiome differences between non-obese and obese subjects using a Western NAFLD cohort. | Nature Communications

Fig. 6: Validation of gut-microbiome differences between non-obese and obese subjects using a Western NAFLD cohort.

From: Distinct signatures of gut microbiome and metabolites associated with significant fibrosis in non-obese NAFLD

Fig. 6

a Abundance of Veillonellaceae and Ruminococcaceae stratified by obesity status and advanced fibrosis (*P = 0.0120, n = 107 for non-obese, and n = 61 for obese). b ROC curves using the combination of two selected bacteria (Veillonellaceae and Ruminococcaceae) were plotted for the diagnosis of advanced fibrosis in non-obese and obese subjects, and the areas under the ROC curve (AUCs) were calculated. The box plots indicate the median, 25th to 75th percentiles (boxes), and 10th to 90th percentiles (whiskers). Statistical analysis was performed using a two-sided Mann–Whitney test. *P < 0.05. ns, not significant.

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