Fig. 6: IR and IS responses to seasons.
From: Deep longitudinal multiomics profiling reveals two biological seasonal patterns in California
a 187 analytes show seasonality difference between IR and IS, of which 116 features exhibit global differences between IR and IS throughout the entire year and 71 features show the statistical significance during part of the year (OmicsLonDA permutation test p ≤ 0.05). b Examples of omics analytes that show significant differential abundance/expression between IR and IS subjects across the year. For each analyte, the orange curve represents fitted curve for IR, and dark blue curve represents the fitted curve for IS subjects. Gray shaded area between the two curves highlights time intervals when the corresponding feature is significantly different between the two groups (IR and IS). c Significant time intervals of analytes that show differences between IR and IS in part of the year. Each row represents an analyte, and the shaded area represents the time of the year that each corresponding feature shows a significant difference between IR (orange) and IS (blue) based on OmicsLonDA test statistics of each time interval.
