Table 2 Sample summary.

From: Prostate cancer evolution from multilineage primary to single lineage metastases with implications for liquid biopsy

Samples

Entering study

Failed library prep

EGA dataset A

EGA dataset B

Body fluid

37

7

25

5

 

(Serum 12, plasma 7, whole blood 5, CSF 3, urine 6, pericardial fluid 2, pleural fluid 2)

(Plasma 1, urine 2, pericardial fluid 2, pleural fluid 2)

(Serum 12, plasma 6, whole blood 4, CSF 2)

(Whole blood 1, urine 4)

Frozen tissue

53

0

52

1

 

(Metastatic PCa 47, primary PCa 5, kidney NL 1)

 

(Metastatic PCa 47, primary PCa 5)

(Kidney NL 1)

Paraffin embedded (PE) tissue

73

6

41

26

 

(Metastatic PCa 9, primary PCa 42, normal prostate 18, normal lymph node 1, BPH 2, PIN 1)

(Metastatic PCa 1, primary PCa 4, normal prostate 1)

Metastatic PCa 8, primary PCa 33)

(Primary PCa 5, noncancerous prostate and lymph node 21)

Total

163

13

118

32

  1. Sequence data from 150 samples where library creation succeeded were analysed and are submitted to EGA. 118 samples central to findings presented in the main text are contained in EGA dataset A. Data from 32 samples with important background control and other findings are included in EGA dataset B and are discussed in the Sample Qualification section and detailed in Supplementary Data 2, 3 and 7.