Fig. 9: Polysynaptic inhibition between striatal ChINs enhances synchrony and broadcasts the pause signal to neighboring ChINs. | Nature Communications

Fig. 9: Polysynaptic inhibition between striatal ChINs enhances synchrony and broadcasts the pause signal to neighboring ChINs.

From: Polysynaptic inhibition between striatal cholinergic interneurons shapes their network activity patterns in a dopamine-dependent manner

Fig. 9

Top: following common excitatory input in a subset of ChINs, polysynaptic inhibition can broadcast a synchronous pause in the bursting population (left ChIN) as well as neighboring ChINs that did not burst following the excitatory input (right ChINs). Bottom: presynaptic ChINs can promote synchrony in postsynaptic ChINs by increasing the likelihood of synchronous discharge through rebound spiking after a concurrent inhibition. The scheme illustrates the concurrent discharge following a polysynaptic inhibitory event.

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