Fig. 1: Manhattan plots for the GWAS meta-analysis of the standardized mammographic density phenotypes for 24,192 women with Hologic or GE full-field digital mammography exams. | Nature Communications

Fig. 1: Manhattan plots for the GWAS meta-analysis of the standardized mammographic density phenotypes for 24,192 women with Hologic or GE full-field digital mammography exams.

From: Identification of 31 loci for mammographic density phenotypes and their associations with breast cancer risk

Fig. 1

Blue denotes new loci, red denotes previously identified loci, and purple denotes new phenotypic associations at previously identified loci. A new DA SNP in MTMR11 was in linkage disequilibrium (r2 = 0.85) with a previously identified PD SNP in between SV2A and SF3B4. A new NDA SNP in MRTFA was in linkage disequilibrium (r2 = 0.39) with a previously identified DA SNP in SGSM3. The ZNF365 locus contains two independent subregions (r2 = 0.07) associated with DA or NDA, respectively, as well as with PD.

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