Table 1 Reference metrics and associated acceptance criteria from the system suitability QC tests.

From: Standardization and harmonization of distributed multi-center proteotype analysis supporting precision medicine studies

 

Acceptance criteria

Median LC peak width

17 ± 3 s

Number of MS1 data points across LC peak

8–11

Number of MS2 data points across LC peak

3–4

Precursor IDs (1% FDR)

>48000

Protein IDs (1% FDR)

>5000

Inter-injection median CV of precursors

≤15%