Fig. 3: Inflammatory cytokine signature in serum from patients with SOCS1 mutations.
From: Early-onset autoimmunity associated with SOCS1 haploinsufficiency
Cytokine array analysis of serum from patients with SOCS1 insufficiency, controls, patients with STAT1 GOF mutations, and patients with STAT3 GOF mutations. Gray: symptomatic patients; white: asymptomatic carriers. Decimal logarithms of the values determined in a multiplex bead assay were color-coded as follows: for each individual cytokine, median values obtained in the 17 HCs were defined as 0 (white). The X-fold standard deviation above this median (0 to +4, coded in red) or below this median (0 to −4, coded in blue) is shown with the individual squares. The color code was arbitrarily truncated at ±4 SDs.
