Fig. 5: Increased single-cell LINC00607–SERPINE1 co-expression in dysfunctional ECs. | Nature Communications

Fig. 5: Increased single-cell LINC00607SERPINE1 co-expression in dysfunctional ECs.

From: Stress-induced RNA–chromatin interactions promote endothelial dysfunction

Fig. 5

a H + T Day 7 induced interactions (edges) between Linc607SE (yellow node) and hub SEs (red nodes). b, c Odds ratio (y-axis) between single-cell co-expression levels and the health status of ECs, including H + T vs. control ECs (b) and diabetic (T2D) vs. healthy vascular endothelium (c). Each dot corresponds to a gene in any Linc607SE-interating SE (a). A large odds ratio corresponds to a positive association between dysfunction (H + T Day 7 for b and diabetic for c) and the single-cell co-expression of this gene with LINC00607. Source data are provided as a Source data file.

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