Fig. 8: Transiently enhanced HFO synchrony among task-relevant areas during visuomotor processing.

a HFO amplitude is increased above baseline levels in a subset of SEEG electrode contacts (representative subject, contacts sorted by the mean HFO amplitude in 150–350 ms time window, frequencies averaged across 110–430 Hz, z-score normalized by the pre-stimulus baseline from –500 ms to –10 ms). The vertical line plot indicates the mean (thick line) and individual (thin lines) sorted HFO responses for all subjects in the 150–350 ms window. The horizontal line plot shows the mean (thick line) and individual (thin lines) temporal evolution of the HFO responses for the top 5% of electrode contacts for all subjects. b Change in PLV from baseline levels among the top 5% of electrode contacts (200 ms time windows for frequencies from 110 to 450 Hz frequencies for the same subject that is shown in a). c Three largest positive (red) and negative (blue) time-frequency clusters for the representative subject (threshold for PLV change: 0.001). d Superposition of the three largest positive (left) and negative (right) clusters of all subjects (K indicates the fraction of subjects with a cluster contributing to each time-frequency element). e Sum of the time-frequency elements in the three largest clusters as a function of the clustering threshold for the positive and negative clusters (thick lines, group mean; thin lines, individual subjects; black dashed line indicates 95%-ile of the cluster sizes found with identical analysis of surrogate data). f Difference of total cluster-size areas (area-under curves in e from threshold of 0 to inf) from threshold between the data and surrogate mean for varying fractions of contacts used in synchrony estimation (averaged across subjects, shaded areas indicate bootstrapped 5 and 95 %-ile confidence limits of the means). g Cluster-size areas (data minus surrogate as in f) for synchronization evaluated in 5% contact sets along the Task+ … Task– axis defined by sorted HFO amplitudes (black lines indicate the 95%-ile (thick line) and mean (thin line) of surrogate data.