Fig. 3: SCML2 cross-linking to nucleosomes.
From: Analysis of protein-DNA interactions in chromatin by UV induced cross-linking and mass spectrometry
a Cysteine and histidine cross-links to deoxyribose-phosphates identified in UV-irradiated samples of the SCML2-nucleosome complex are highlighted with yellow or orange stars, respectively. SCML2 structure is shown schematically and protein domains are indicated. b Cross-links to deoxyribose-phosphate identified in SCML2-nucleosome+H1 irradiated samples are shown as in a). Cross-links to thymine are highlighted with red stars and marked by residue number. Non-marked stars represent cross-links to deoxyribose as described under a. Domains: MBT malignant brain tumor, RBR RING-BetweenRING-RING, SLED Scm-Like Embedded Domain, SAM sterile alpha motif, preSAM-aa466-616.
