Fig. 3: Patient symptoms are reflected in immune cell variations. | Nature Communications

Fig. 3: Patient symptoms are reflected in immune cell variations.

From: Whole blood immunophenotyping uncovers immature neutrophil-to-VD2 T-cell ratio as an early marker for severe COVID-19

Fig. 3

a Schematic representation of clinical symptoms in the patient cohort. b Absolute counts of T-cells across the severity. c Absolute counts of antigen presenting cells across the severity. d gMFI of activation markers on antigen presenting cells. e Absolute counts and frequency in neutrophil compartments. Data presented are from individual human acute COVID-19 patients n = 54 from panels a, b and c, separated according to clinical severity: no pneumonia n = 19, pneumonia no hypoxia n = 11, pneumonia with hypoxia no ICU n = 9, pneumonia with hypoxia with ICU n = 15. Scatter dot plots are presented with mean ± SD. Absolute counts and frequency were analysed by Kruskal–Wallis with Dunn multiple testing correction, gMFI was analysed by Brown–Forsythe and Welch ANOVA with Dunnett T3 multiple testing correction. *p < 0.05, **p < 0.01, ***p < 0.001. Data available in source data file, exact p-values are given in Supplementary Data 1.

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