Fig. 1: Immunohistochemical analysis of ACE2 protein localization across human tissues using multiple anti-ACE2 antibodies.
From: ACE2 localizes to the respiratory cilia and is not increased by ACE inhibitors or ARBs
Representative images of human tissues on a tissue microarray (TMA) stained by chromogenic immunohistochemistry using antibodies targeting the ACE2 protein (brown) and counterstained with hematoxylin (blue). Highest ACE2 expression was observed in the villi of the intestinal tract (jejunum), renal tubules, testis, and glandular cells in the seminal vesicle. Minimal to no/non-specific staining can be seen in the heart, stomach, spleen, skin, and liver. Staining of lung pneumocytes was observed using Abcam ab15348, and less specifically with Sigma HPA000288 (Fig. 2b; Supplementary Table 1). Scale bars: 100 μm.
