Table 1 Demographic summary of patients.
From: ACE2 localizes to the respiratory cilia and is not increased by ACE inhibitors or ARBs
Control | ARBs | ACEI | p value | ||
---|---|---|---|---|---|
Stanford (n = 28) | Number of patients | 16 | 7 | 5 | – |
Age (years) | 53 ± 18 | 68 ± 17 | 66 ± 12 | 0.09 | |
Sex | – | – | – | 0.90 | |
Male, n (%) | 10 (63) | 5 (71) | 3 (60) | – | |
Female, n (%) | 6 (38) | 2 (29) | 2 (40) | – | |
Smoking | – | – | – | 0.89 | |
Current, n (%) | 0 (0) | 0 (0) | 0 (0) | – | |
Former, n (%) | 5 (31) | 2 (29) | 1 (20) | – | |
No, n (%) | 11 (69) | 5 (71) | 4 (80) | – | |
Hypertension, n (%) | 6 (38) | 7 (100) | 5 (100) | <0.01 | |
Sinus diseases | – | – | – | 0.27 | |
Control, n (%) | 5 (31) | 1 (14) | 0 (0) | – | |
CRSsNP, n (%) | 4 (25) | 1 (14) | 3 (60) | – | |
CRSwNP, n (%) | 7 (44) | 5 (71) | 2 (40) | – | |
NTUH (n = 31) | Number of patients | 19 | 12 | – | – |
Age (years) | 62 ± 11 | 62 ± 12 | – | 0.93 | |
Sex | – | – | – | 0.48 | |
Male, n (%) | 10 (53) | 8 (67) | – | – | |
Female, n (%) | 9 (47) | 4 (33) | – | – | |
Smoking | – | – | – | 0.70 | |
Current, n (%) | 1 (5) | 0 (0) | – | – | |
Former, n (%) | 2 (11) | 1 (8) | – | – | |
No, n (%) | 16 (84) | 11 (92) | – | – | |
Hypertension, n (%) | 10 (53) | 12 (100) | – | <0.01 | |
Sinus diseases | – | 0.23 | |||
Control, n (%) | 4 (21) | 0 (0) | – | – | |
CRSsNP, n (%) | 1 (5) | 1 (8) | – | – | |
CRSwNP, n (%) | 14 (74) | 11 (92) | – | – | |
CMUH (n = 25) | Number of patients | 17 | 8 | – | – |
Age (years) | 50 ± 10 | 62 ± 6 | – | <0.05 | |
Sex | – | – | – | 0.20 | |
Male, n (%) | 7 (41) | 6 (75) | – | – | |
Female, n (%) | 10 (59) | 2 (25) | – | – | |
Smoking | – | – | – | 0.29 | |
Current, n (%) | 3 (18) | 3 (38) | – | – | |
Former, n (%) | 2 (12) | 2 (25) | – | – | |
No, n (%) | 12 (71) | 3 (38) | – | – | |
Hypertension, n (%) | 3 (18) | 8 (100) | – | < 0.01 | |
Sinus diseases | – | – | – | 0.49 | |
Control, n (%) | 6 (35) | 1 (13) | − | – | |
CRSsNP, n (%) | 5 (29) | 3 (38) | − | – | |
CRSwNP, n (%) | 6 (35) | 4 (50) | − | – |