Table 1 Comparison of prior DNA storage work with key parameters.

From: Low cost DNA data storage using photolithographic synthesis and advanced information reconstruction and error correction

Parameter

Church et al.

Goldman et al.

Grass et al.

Erlich et al.

Organick et al.

Lee et al.

This work

Synthesis method

Deposition (Phosphoramidite)

Deposition (Phosphoramidite)

Electrochemistry (Phosphoramidite)

Deposition (Phosphoramidite)

Deposition (Phosphoramidite)

Column (Enzymatic)

Light-directed (Phosphoramidite)

Input data (MB)

0.6511

0.7511

0.0811

2.1511

200.213

1.2 x \(10^{ - 5}\)

0.1

Net info (bits nt−1)

0.8311

0.3311

1.1411

1.5711

1.1013

0.46

0.94

Info incl. primers (bits nt−1)

0.6013

0.1913

0.8613

1.1813

0.8113

0.46

0.94

Cost (US$ MB−1)

11,6502

12,4001

31,25012

326011

5610

7010*

530*

  1. Note that net information density excludes the primers. Post-synthesis costs, such as library preparation and sequencing are not included in the cost calculations. Detailed information about calculations can be taken from Supplementary Note 5.
  2. *Only consumable costs (at non-industry rates), no overhead or library preparation costs considered.
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