Fig. 3: Variation in the thalianol cluster within A. thaliana species.
From: Formation and diversification of a paradigm biosynthetic gene cluster in plants
a A. thaliana accessions identified from the Arabidopsis 1001 genome sequence database as lacking homologs to thalianol cluster genes (aligned with the Col-0 reference genome). Deletions are indicated by gray bars. The three different types of deletion patterns (lacking one or more cluster genes) are indicated by colored triangles. A fully assembled region from long-read re-sequencing of the accession Lillö-1 (asterisked) showing an inversion in this region is illustrated at the bottom. b Chromosomal inversions in the thalianol region from genomes of representative de novo assembled A. thaliana accessions. c Frequencies of Col-0-like and contiguous thalianol clusters in the genomes of 21 de novo assembled A. thaliana accessions. Accessions Sha and Eri are newly PacBio-sequenced accessions that were not included in the 1135 short read sequenced collections17. d Phylogenetic tree for 1135 A. thaliana accessions. Phylogenetic distances were calculated based on 28,775 filtered SNPs using RAxML40. Tree node support (>90%) is indicated by pink dots on branches (1000 bootstrap replicates). Accessions with thalianol pathway gene deletions and chromosomal inversion variations are indicated. Other monophyletic groups are collapsed.
