Fig. 2: The P0 IFE basal cell layer contains two distinct cell populations. | Nature Communications

Fig. 2: The P0 IFE basal cell layer contains two distinct cell populations.

From: Murine interfollicular epidermal differentiation is gradualistic with GRHL3 controlling progression from stem to transition cell states

Fig. 2

a Expression heatmap of unique gene signatures for each of the two basal IFE clusters. Blue arrows highlight select differentially expressed genes between the two basal clusters. Gene lists in Supplementary Data 1. b Expression level of select genes, which are enriched in either IFE.B1 or IFE.B2, projected onto tSNE for the two basal clusters. c Heatmap showing the correlation between cells for SC3 clustering (1, 2; red, blue) and Seurat clustering (IFE.B1, IFE.B2; purple, green). d RNA-FISH for Wnt4 in the P0 IFE. White arrowheads, Wnt4-high cells; blue arrowheads, Wnt4-low cells; white broken line, basal lamina; E epidermis, D dermis, HF hair follicle. Scale bar = 10 µm, representative image for N = 5.

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