Fig. 1: Severity levels of COVID-19 and schematic diagram of the baseline analyses.
From: Disease burden and clinical severity of the first pandemic wave of COVID-19 in Wuhan, China
a Severity levels of infections with SARS-CoV-2 and parameters of interest. Each level is assumed to be a subset of the level below. sCFR symptomatic case-fatality risk, sCHR symptomatic case-hospitalization risk, mCFR medically attended case-fatality risk, mCHR medically attended case-hospitalization risk, HFR hospitalization-fatality risk. b Schematic diagram of the baseline analyses. Data source of COVID-19 cases in Wuhan: D1) 32,583 laboratory-confirmed COVID-19 cases as of March 84, D2) 17,365 clinically-diagnosed COVID-19 cases during February 9–194, D3)daily number of laboratory-confirmed cases on March 9–April 243, D4) total number of COVID-19 deaths as of April 24 obtained from the Hubei Health Commission3, D5) 325 laboratory-confirmed cases and D6) 1290 deaths were added as of April 16 through a comprehensive and systematic verification by Wuhan Authorities3, and D7) 16,781 laboratory-confirmed cases identified through universal screening10,11. Pse: RT-PCR sensitivity12. Pmed.care: proportion of seeking medical assistance among patients suffering from acute respiratory infections13. (Red, blue, and green arrows separately denote the data flow from laboratory-confirmed cases of passive surveillance, clinically-diagnosed cases, and laboratory-confirmed cases of active screenings).
