Fig. 6: Widespread occurrence of dCache_1-containing AI-2 receptors in bacteria and archaea.
From: Sensing of autoinducer-2 by functionally distinct receptors in prokaryotes
a A conservation pattern found in dCache_1 domains. Multiple alignment analysis of 18970 dCache_1 domains was performed with ClustalW embedded in MEGA7 (Supplementary Data 3). The region corresponding to the active pocket of PctA-LBD (residues 100–175) is illustrated using WebLogo 3. Cyan arrows above the WebLogo denote the five highly conserved positions corresponding to R126, W128, Y144, D146, and D173 of PctA. b Distribution of 1535 dCache_1-containing proteins with all the five conserved residues corresponding to R126, W128, Y144, D146, and D173 of PctA at the phylum level in prokaryotes. The number of occurrences for each type of signal transduction proteins is listed in parentheses.
