Fig. 4: Contributions of key tertiary interactions to the directional mechanical stability of ZIKV xrRNA1.

a–c Secondary structures (left), representative current blockade traces (middle), and the respective dwell time histogram (right) for the directional mechanical unfolding of 5′A36-xrRNA1-G3C (a), 5′A36-xrRNA1-PK2mut (b), and 5′A36-xrRNA1-X-∆P4(c) in the α-HL nanopore.