Fig. 5: Mechanical anisotropy of ZIKV xrRNA1 is mainly dictated by its ring-like structure.

a Plots of the dwell time for the unfolding and translocation of 5′A36-xrRNA1-X or 3′A36-xrRNA1-X in the α-HL nanopore against Mg2+ concentrations. b Plots of the dwell time for the unfolding and translocation of xrRNA1 mutants in the α-HL nanopore in the presence of 5 mM Mg2+. The dwell time for each of 3 independent experiments (n = 3), the mean and SEM are presented as dot, column, and error bar, respectively. Source data for a and b are provided as a Source Data file.