Fig. 7: EOS functions in post-MI heart.
From: Eosinophils improve cardiac function after myocardial infarction
a Schematic illustration of EOS accumulation in the infarct area of mouse heart post-MI. b Summary of EOS function in protecting heart from MI-induced injury by producing Th2 cytokines (e.g., IL4), cationic proteins (mouse mEar1, human ECP and EOS-derived neurotoxin), or other untested molecules to reduce cardiomyocyte apoptosis, cardiac fibroblast activation and fibrotic protein synthesis, and inflammatory cell adhesion and infarct heart accumulation.
