Fig. 3: ci-Ins2 is specifically detected in β cells.
From: A circular RNA generated from an intron of the insulin gene controls insulin secretion
a ci-Ins2 and (b) Ins2 normalized to Hprt1, measured by qPCR, in rat blood cells, plasma, and 19 tissues relative to islet levels. ND = not detected. n = 4 independent experiments. *p < 0.0001 vs. islets by one-way ANOVA and Dunnett post hoc test. c ci-Ins2 (black circles), Ins2 (gray circles), and Gcg (clear circles) normalized to Hprt1, measured by qPCR, in rat α-cells relative to β-cells. n = 5 independent experiments. ***p = 0.000005 (ci-Ins2), ***p = 0.0001 (Ins2), and ***p = 0.0002 (Gcg) vs. β-cells by two-tailed unpaired t-test. a–c Data and mean are represented ± s.d. Source data are provided as a Source Data file.
