Fig. 1: Study overview and randomization.

CONSORT diagram of the number of participants that completed each study visit and provided genital samples, and the distribution of participants on each of the hormonal contraceptive methods analyzed: combined oral contraceptives (COC), the Net-En injection, and the vaginally inserted combined contraceptive ring (CCVR) at crossover and exit. Note that at crossover, some participants could choose their next contraceptive method if assigned to CCVR as their first method. LTFU loss-to-follow-up.