Fig. 7: De novo production of glycyrrhizin in yeast.
From: A cellulose synthase-derived enzyme catalyses 3-O-glucuronosylation in saponin biosynthesis

a Overlay of LC–MS chromatogram showing in vivo production of glycyrrhizin in the yeast strain GL0–3. Signals were compared to authentic standards. Chromatograms were selected based on the theoretical m/z values of glycyrrhetinic acid (GA, 469.3), glycyrrhetinic acid-3-O-monoglucuronide (GA–GlcA, 645.4) and glycyrrhizin (GL, GA–GlcA–GlcA, 821.4). b Glycyrrhizin production by GL0–3. The amount of glycyrrhizin was measured separately from collected cells (circles) and medium (dashed circles) 5 days after induction. Error bars represent SDs (n = 3).