Fig. 1: SMARCA4 mutational spectrum in the FoundationCORE® patient cohort. | Nature Communications

Fig. 1: SMARCA4 mutational spectrum in the FoundationCORE® patient cohort.

From: Functional characterization of SMARCA4 variants identified by targeted exome-sequencing of 131,668 cancer patients

Fig. 1

a SMARCA4 alteration frequency separated by disease ontology (n = 131,668 patients). b Distribution of SMARCA4 mutation types (n = 10,562 variants). c Zygosity of SMARCA4 truncating and nontruncating variants in patients where zygosity was determined (n = 5699 patients). d Mutual exclusivity of SMARCA4 mutations with the aggregate of other BAF genes profiled in the FoundationOne® panel (ARID1A/B, ARID2, PBRM1, SMARCB1, SMARCD1).

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