Fig. 2: Local enhancer e4 is significantly co-amplified with MYCN.
From: Enhancer hijacking determines extrachromosomal circular MYCN amplicon architecture in neuroblastoma
a Co-amplification frequency of the immediate MYCN neighborhood measured using copy-number profiles from 240 MYCN-amplified neuroblastomas (solid line) compared to the expected co-amplification frequencies for randomized MYCN-containing amplicons (dashed line). b Upset plot showing the co-amplification patterns of all five MYCN-specific local enhancers identified in neuroblastoma. c Enrichment for co-amplification with MYCN of genomic regions on 2p (red, co-amplification more frequent than expected by chance; blue, co-amplification less frequent than expected by chance). Source data are provided as a Source Data file.
