Table 1 HERV-derived T cell epitopes identified based on CD8+ T cell recognition in patients and healthy donors.
From: Human endogenous retroviruses form a reservoir of T cell targets in hematological cancers
HERV gene ID | Peptide | HLA | Patients or HDs |
|---|---|---|---|
ERVFRD-1 | WTGTCTIGY | HLA-A01:01 | Patient |
STVCNVTFTV | HLA-A02:01 | Patient | |
LPSNWTGTCTI | HLA-B07:02 | Patient | |
GPIFTNINLM | HLA-B07:02 | Patient | |
GPIFTNINL | HLA-B07:02 | Patient | |
ERVFRD-2 | GPVQVQVPFSM | HLA-B07:02 | Patient |
RPLQRPQPG | HLA-B08:01 | Patient | |
ERVE-3 | YIDTWLQLMLN | HLA-A01:01 | Patient |
SLVSKVWHKV | HLA-A02:01 | Patient | |
ERVFH21-1 | SIMILHRMSL | HLA-B07:02 | Patient |
MILHRMSLLRL | HLA-B08:01 | Patient and healthy donor | |
ERVK-4, ERVK-9, ERVK-15, ERVK-16 | YMRTLLDSI | HLA-A02:01 | Patient |
ERVK-16 | FIWQHRILL | HLA-A02:01 | Patient |
ERVS71-1 | ATCNQSLLTY | HLA-A01:01 | Healthy donor |
RLHQAVPLL | HLA-A02:01 | Patient | |
FLLTSFTTGRV | HLA-A02:01 | Patient | |
ERVH-5 | RPRVLRLISPR | HLA-B07:02 | Patient |
ERVK-7, ERVK-6, ERVK-21 | ITGTWLDAIY | HLA-A01:01 | Healthy donor |
ERVK-6 | GPLLSFSIL | HLA-B07:02 | Patient |
ERVK3-3 | LLIKENLFL | HLA-A02:01 | Patient |
ERVK3-5 | YLKACLTVL | HLA-A02:01 | Patient |
ERVK-5 | QPQAPQQTGAF | HLA-B07:02 | Patient |
ERVK-21 | ALMIVSMVVSL | HLA-B08:01 | Patient |
ERVK-24 | ILVSMDRPWEA | HLA-A02:01 | Patient |
ERVMER61- 1 | LPATVPSLPGL | HLA-B07:02 | Patient |
ERVW-1 | CLISILVSSL | HLA-A02:01 | Patient |
MIGYFFTSCL | HLA-B08:01 | Healthy donor | |
ERVK-12 | VPHPQPPTL | HLA-B07:02 | Healthy donor |
ERVK-14, ERVK-11, ERVK-13, ERVK-3, ERVK-24, ERVK-25, ERVK-8 | DLILRHHLV | HLA-B08:01 | Healthy donor |
