Fig. 5: Plasma, liver, and muscle amino acid content of Lkb1KOlivad mice.
From: Lkb1 suppresses amino acid-driven gluconeogenesis in the liver
a Plasma amino acid concentration in fasted mutant (KO: n = 13, red bar) and fasted control (WT: n = 7, gray bar) mice. b Hepatic amino acid content of fasted mutant mice (KO: n = 10, red bar) and fasted control mice (WT: n = 9, gray bar). c Muscle (tibialis) amino acid content of fasted mutant mice (KO: n = 10, red bar) and fasted control mice (WT: n = 9, gray bar). d Ammonia and urea level in the plasma and ammonia level in the liver of Lkb1KOlivad(KO, n = 13, red bar) and controls (WT, n = 7, gray bar). All data are presented as mean values ± SD. P values were determined by unpaired two-tailed t-test. ns: not significant; *p ≤ 0.05; **p ≤ 0.01; ***p ≤ 0.01. For all the experiments described in this figure, animals were analyzed 15 days after the injection of tamoxifen.
