Fig. 8: H3K27me3 deposition and Ring1B binding at BMP and Wnt ligand gene loci in early stage telencephalic NPCs. | Nature Communications

Fig. 8: H3K27me3 deposition and Ring1B binding at BMP and Wnt ligand gene loci in early stage telencephalic NPCs.

From: The Polycomb group protein Ring1 regulates dorsoventral patterning of the mouse telencephalon

Fig. 8

a The telencephalon was isolated from WT (ICR) mice at E9 for ChIP-qPCR analysis with antibodies to H3K27me3 or to Ring1B. b, c ChIP-qPCR analysis of H3K27me3 deposition (b) and Ring1B binding (c) at the indicated promoters as in (a). Hoxa1 and Hoxd3 were examined as positive controls, and Actb and Gapdh as negative controls. Data are expressed as percentage input and are means ± s.d., n = 3 independent experiments, two-tailed Student’s unpaired t test versus the corresponding value for Actb. Source data are provided as a Source Data file.

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