Fig. 2: Applications on yeast genomes.
From: Computer vision for pattern detection in chromosome contact maps
a Zoom-in of the contact map of chromosome 5 of S. cerevisiae with synchronised ChIP-Seq signal of Scc1 protein (cohesin) at 2 kb resolution with detected loops and border patterns,8. The darker, the more contacts. b Pileup plots of windows centered on detected loops with the number of detections. Barplots of the proportion of Scc1 peaks for anchors of detected loops and associated p-value (Fisher test, two-sided). c Loop spectrum showing scores in function of the loop size in S. cerevisiae (974 loops) and S. pombe (1484 loops). Curves represent lowess-smoothed data for easier interpretation with 95% confidence intervals. d Number of loops detected only in G1 phase, M phase, or in both. For each category, the pileup of each set of coordinates is shown for both G1 and M conditions (mitotic data8 subsampled from 44M to 5.8M contacts for comparison with G17).
