Fig. 7: Selected metabolic features of the porcine colon microbiome in response to AcGGM dietary intervention, as inferred from genome and proteome comparisons.
From: Microbiota-directed fibre activates both targeted and secondary metabolic shifts in the distal gut
The different metabolic pathways (fiber deconstruction, glycolysis, pentose-phosphate pathway, and SCFA production) are displayed for each population MAG. Graphical representation of pathways, enzymes, CAZymes, and cellular features are based on functional annotations that are depicted as numbered or abbreviated gene boxes, which are additionally listed in Supplementary Data 6. Metaproteomic analysis (detected genes and enzyme complexes) is highlighted according to the different LFQ values of the detected proteins sampled at a single time-point (28 days) either from animals fed the control or 4% AcGGM diet (green perforated boxes). The main dietary fibers (starches, xylans, glucans, and mannans), SCFAs (butyrate, acetate, propionate), and intermediates like lactate and succinate are represented by large colored arrows. GTBD-Tk inferred taxonomy is included (recently reclassified Roseburia species are denoted as Agathobacter). Gene names and abbreviations are also provided in Supplementary Data 6.
