Fig. 1: Faecal microbiota of COPD patients (n = 28) can be distinguished from that of healthy individuals (n = 29) using 16S rRNA gene amplicon sequencing. | Nature Communications

Fig. 1: Faecal microbiota of COPD patients (n = 28) can be distinguished from that of healthy individuals (n = 29) using 16S rRNA gene amplicon sequencing.

From: Disease-associated gut microbiome and metabolome changes in patients with chronic obstructive pulmonary disease

Fig. 1

a Principal component (PC) analysis undertaken at the sequence variant level using read counts transformed using log-cumulative-sum scaling. b Multivariate sparse partial least-squares discriminant analysis (sPLS-DA) of read counts transformed using log-cumulative-sum scaling at the sequence variant level. c Sequence variants contributing to separation along with component 1 of sPLS-DA from b. Bar length indicates loading coefficient weight of selected genomes, ranked by importance, bottom to top; bar colour indicates the group in which the sequence variant has the highest median abundance, red = COPD, blue = healthy. d Heatmap of read counts transformed using log-cumulative-sum scaling of discriminatory sequence variants identified along with component 1 of sPLS-DA from (b).

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