Fig. 2: Metagenomic sequencing-based exploration of COPD-associated (n = 28) faecal microbiomes supports distinction from those of healthy individuals (n = 29). | Nature Communications

Fig. 2: Metagenomic sequencing-based exploration of COPD-associated (n = 28) faecal microbiomes supports distinction from those of healthy individuals (n = 29).

From: Disease-associated gut microbiome and metabolome changes in patients with chronic obstructive pulmonary disease

Fig. 2

a Multivariate sparse partial least-squares discriminant analysis (sPLS-DA) of read-mapping-based relative abundance at the genome level of the faecal microbiome, filtered for genomes with minimum 0.05% relative abundance in at least one sample. b Genomes contributing to separation along with component 1 of sPLS-DA from (a). Bar length indicates loading coefficient weight of selected genomes, ranked by importance, bottom to top; bar colour indicates the group in which the genome has the highest median abundance, red = COPD, blue = healthy. c Heatmap of discriminatory genomes along component 1 of sPLS-DA from (a). Data are centred with log-ratio-transformed relative abundance.

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