Fig. 5: Filament binding by drebrin alters utrophin ABD mutant dwell times. | Nature Communications

Fig. 5: Filament binding by drebrin alters utrophin ABD mutant dwell times.

From: Biased localization of actin binding proteins by actin filament conformation

Fig. 5

a Single molecule binding kinetics in the presence of 200 nM of the actin-binding domain of the protein drebrin (drebrin 1–300). Comparisons of the first timescale b second timescale c and relative amplitudes d from a double exponential fit to the cumulative distribution functions for the different constructs. Error bars are the standard deviation around the mean of 3 technical replicates. Conditions were compared using a two-tailed students t-test, with p < 0.05 denoted by a star (*).

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