Table 1 Sample characteristics of the brain and blood cohorts included in the meta-analysis.
Dataset | Tissue | Sample size | Women N (%) | Cases N (%) | Age at death mean (SD) | Accession |
|---|---|---|---|---|---|---|
Brain samples cohort | ||||||
(1) ROSMAP cohort | PFC | 726 | 461 (63.5%) | 581 (80.0%) | 86.3 (4.8) | Synapse: syn3157275 |
(2) Mt. Sinai cohort | PFC | 141 | 88 (62.4%) | 85 (60.3%) | 85.8 (7.8) | GEO: GSE80970 |
(3) London cohort | PFC | 107 | 64 (59.8%) | 80 (74.8%) | 84.6 (9.0) | GEO: GSE59685 |
(4) Gasparoni cohort | PFC | 56 | 29 (51.8%) | 36 (64.3%) | 73.6 (14.7) | GEO: GSE66351 |
(5) London cohort | whole blood | 69 | 44 (63.8%) | 59 (85.5%) | 83.6 (6.2)* | GEO: GSE59685 |
