Fig. 1: Manhattan plot depicting loci associated with childhood asthma with severe exacerbations in the discovery genome-wide meta-analysis. | Nature Communications

Fig. 1: Manhattan plot depicting loci associated with childhood asthma with severe exacerbations in the discovery genome-wide meta-analysis.

From: FUT2–ABO epistasis increases the risk of early childhood asthma and Streptococcus pneumoniae respiratory illnesses

Fig. 1

Association P value (suggestive threshold line in black): 1 × 10−4, (genome-wide threshold line in red): 5.0 × 10−8. Associations are from fixed-effect meta-analyses based on logistic regression models adjusted for sex and the first ten principal components. Ndiscovery = 68,281 individuals (\(N_{{\mathrm{COPSAC}}_{\mathrm{severe}}}\) = 6532 and NiPSYCH = 61,749).

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