Fig. 2: Association “heatmaps” for FUT2 (rs601338)–ABO (rs505922) genotype combinations. | Nature Communications

Fig. 2: Association “heatmaps” for FUT2 (rs601338)–ABO (rs505922) genotype combinations.

From: FUT2–ABO epistasis increases the risk of early childhood asthma and Streptococcus pneumoniae respiratory illnesses

Fig. 2

The risk of asthma (OR or odds ratio) was calculated for each genotype combination in relation to the reference group (FUT2 [AA] and ABO [TT]). Heatmaps are shown for a the COPSACsevere study (discovery) and b the COPSAC birth cohorts (replication). N: number of participants in each group. The logistic regression model in a is adjusted for sex and ten principal components. The model in b is adjusted for sex and cohort status.

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